Circulating tumor cells of colorectal cancer
نویسندگان
چکیده
As the prognosis of colorectal cancer (CRC) patients is mostly determined by the occurrence of distant metastases, circulating tumor cells (CTC) may be an attractive therapeutic target. Despite the rarity of CRCderived CTC, considerable progress has recently been made in the investigation of their molecular characteristics. In this review article we present recent clinical and molecular data on CRC-derived CTC, discuss their implications and propose a new phenotypic state of CTC, the immune-evasive state (IES).
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